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Gang Pei Selected Research

Proteins (Proteins, Gene)

11/2018[Study on effects of total saponins from Lilii Bulbus on proliferation, apoptosis, invasion and metastasis of lung cancer cells and its preliminary mechanism].
10/2018α-secretase ADAM10 physically interacts with β-secretase BACE1 in neurons and regulates CHL1 proteolysis.
1/2018Polysaccharide extracted from Portulacae Oleracea L. exerts protective effects against dextran sulfate sodium-induced colitis through inhibition of NF-κB.
1/2018NF-κB directly regulates β-arrestin-1 expression and forms a negative feedback circuit in TNF-α-induced cell death.
1/2016An Anti-Parkinson's Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-β Generation and γ-Secretase Activity.
2/2015β-arrestin1 is critical for the full activation of NLRP3 and NLRC4 inflammasomes.
8/2011Beta-arrestin-1 protein represses diet-induced obesity.
5/2007Receptor tyrosine kinases positively regulate BACE activity and Amyloid-beta production through enhancing BACE internalization.
10/2004The spike protein of severe acute respiratory syndrome (SARS) is cleaved in virus infected Vero-E6 cells.
9/2004Inhibition of SNAP-25 phosphorylation at Ser187 is involved in chronic morphine-induced down-regulation of SNARE complex formation.
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Gang Pei Research Topics

Disease

18Alzheimer Disease (Alzheimer's Disease)
01/2022 - 12/2006
8Infections
06/2021 - 07/2002
8Inflammation (Inflammations)
06/2021 - 12/2009
6Neoplasms (Cancer)
02/2020 - 02/2003
6Neurodegenerative Diseases (Neurodegenerative Disease)
01/2019 - 03/2013
5Autoimmune Diseases (Autoimmune Disease)
07/2015 - 02/2003
4Neoplasm Metastasis (Metastasis)
11/2018 - 07/2002
4Multiple Sclerosis
12/2013 - 08/2007
3Tuberculosis (Tuberculoses)
01/2021 - 01/2020
3Cognitive Dysfunction
01/2019 - 01/2014
3Mycoses (Diseases, Fungus)
09/2016 - 03/2007
3Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
12/2013 - 08/2007
3Insulin Resistance
08/2011 - 02/2009
3Amyloid Plaque
12/2009 - 12/2006
3Opioid-Related Disorders (Opiate Addiction)
09/2004 - 03/2002
2Glioblastoma (Glioblastoma Multiforme)
02/2020 - 01/2019
2Neuroinflammatory Diseases
01/2018 - 01/2017
2Virus Diseases (Viral Diseases)
01/2017 - 01/2004
2Parkinson Disease (Parkinson's Disease)
01/2017 - 01/2016
2Experimental Arthritis
07/2015 - 04/2013
2Rheumatoid Arthritis
04/2013 - 05/2010
2Pain (Aches)
01/2012 - 08/2005
2Obesity
08/2011 - 08/2011
2Substance-Related Disorders (Drug Abuse)
03/2009 - 03/2002
2Severe Acute Respiratory Syndrome
10/2004 - 06/2003
1Porcine Reproductive and Respiratory Syndrome (PRRS)
06/2021
1Liver Cirrhosis (Hepatic Cirrhosis)
07/2020
1Pulmonary Tuberculosis
01/2020
1Mitochondrial Diseases (Mitochondrial Disease)
01/2020
1Retinoblastoma (Glioblastoma, Retinal)
01/2019
1Bites and Stings (Sting)
01/2019
1Carcinogenesis
11/2018
1Genomic Instability
11/2018
1Lung Neoplasms (Lung Cancer)
11/2018
1Dehydration (Water Stress)
09/2018
1Diarrhea
01/2018
1Colitis
01/2018
1Weight Loss (Weight Reduction)
01/2018
1Granuloma
01/2018
1Memory Disorders (Memory Loss)
01/2017
1Listeriosis (Listeria Infection)
01/2017
1Dyskinesias (Dyskinesia)
01/2017

Drug/Important Bio-Agent (IBA)

14Amyloid (Amyloid Fibrils)IBA
01/2020 - 05/2007
11Proteins (Proteins, Gene)FDA Link
11/2018 - 06/2003
10Pharmaceutical PreparationsIBA
01/2021 - 09/2006
8Amyloid Precursor Protein Secretases (beta-Secretase)IBA
10/2018 - 12/2006
5CytokinesIBA
06/2021 - 02/2006
4beta-Arrestin 1IBA
01/2017 - 08/2007
4Chemokine ReceptorsIBA
07/2015 - 02/2002
4G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
02/2015 - 07/2002
3DNA (Deoxyribonucleic Acid)IBA
01/2019 - 11/2018
3Polysaccharides (Glycans)IBA
01/2018 - 01/2017
3ArrestinsIBA
01/2018 - 01/2013
3Glucose (Dextrose)FDA LinkGeneric
09/2014 - 08/2011
3Amyloid beta-PeptidesIBA
02/2010 - 12/2006
3Morphine (MS Contin)FDA LinkGeneric
03/2009 - 06/2003
3beta-ArrestinsIBA
08/2008 - 02/2006
2NucleotidesIBA
06/2021 - 02/2015
2ArrestinIBA
09/2014 - 12/2013
2Interleukin-17 (Interleukin 17)IBA
04/2013 - 12/2009
2MicroRNAs (MicroRNA)IBA
05/2010 - 12/2009
2Transforming Growth Factor beta1 (TGF beta 1)IBA
02/2008 - 12/2005
2Peptides (Polypeptides)IBA
05/2007 - 06/2003
2Pertussis ToxinIBA
09/2003 - 02/2003
2Opiate AlkaloidsIBA
06/2003 - 03/2002
1Apolipoprotein E4IBA
01/2022
1Pattern Recognition ReceptorsIBA
06/2021
1NLR ProteinsIBA
06/2021
1ChemokinesIBA
06/2021
1arabinogalactanIBA
01/2021
1sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
01/2021
1Matrix Metalloproteinases (MMPs)IBA
01/2021
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
12/2020
1Carbon Tetrachloride (Tetrachloromethane)IBA
07/2020
1TriterpenesIBA
07/2020
1Nonprescription Drugs (Patent Medicines)IBA
07/2020
1AcidsIBA
07/2020
1Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
01/2020
1Sirtuin 3IBA
01/2020
1AntioxidantsIBA
01/2020
1Oxidants (Oxidizing Agents)IBA
01/2020
1Adenosine Monophosphate (AMP)IBA
01/2019
1Mitochondrial DNA (mtDNA)IBA
01/2019
1Interferon Type IIBA
01/2019
1Protein Kinases (Protein Kinase)IBA
01/2019
1SaponinsIBA
11/2018
1cyclic guanosine monophosphate-adenosine monophosphateIBA
11/2018
1Proliferating Cell Nuclear Antigen (PCNA)IBA
11/2018
1Xylose (D-Xylose)FDA Link
09/2018
1SurvivinIBA
01/2018
1Interleukin-10 (Interleukin 10)IBA
01/2018
1Dextran SulfateIBA
01/2018
1Dopamine D2 Receptors (Dopamine D2 Receptor)IBA
01/2017
1Piribedil (Trivastal)IBA
01/2017
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2017
1Levodopa (L Dopa)FDA LinkGeneric
01/2017

Therapy/Procedure

4Therapeutics
11/2018 - 03/2007
3Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2018 - 01/2015
2Oral Administration
01/2019 - 01/2014
1Precision Medicine
01/2018